Paraxanthine pouches are smokeless oral pouches built around paraxanthine (1,7-dimethylxanthine) — the molecule your liver converts roughly 80% of caffeine into, and the one responsible for most of caffeine’s alertness and focus benefits. Delivered directly via buccal absorption, paraxanthine skips the liver-conversion step, has a shorter ~3.4-hour half-life than caffeine’s 5–6 hours, produces significantly less jitter and anxiety at equivalent doses, and shows less tolerance build-up in early studies. Plopii Focus Pouches are the flagship paraxanthine pouch: 120 mg of paraxanthine paired with a dual choline nootropic stack (Alpha-GPC + citicoline) plus L-theanine, Panax ginseng, L-tyrosine, and B vitamins — 100% nicotine-free and tobacco-free, patent-pending, assembled in Brooklyn, NY. Read the paraxanthine ingredient deep-dive, compare paraxanthine vs caffeine head-to-head, explore the science behind the formula, or browse all nicotine-free pouches.